Senior Research Associate, Tumor Immunology

Company: Agenus, Inc.
Location: Lexington, MA
Posted on: January 26, 2016

Job Description:

Duties: Evaluate novel therapies in the field of cancer immunology. Work

closely with discovery scientists to advance research-stage programs

into early clinical development, providing both scientific and technical

expertise including: develop novel functional assays to support

discovery project development. MoA (mechanism of action) studies to

better understand target and therapeutic biology. Explore combinatorial

strategies to support identification of companion diagnostics. Make use

of multiple assays including: multi-parameter flow cytometry, FACS

(fluorescence-activated cell sorting), ELISA (enzyme-linked

immunosorbent assay), qPCR as well as cytotoxicity, cytokine release,

and proliferation readouts. Undertake daily literature searches to help

expand knowledge surrounding target biology. Present scientific data as

well as articles of interest to the group. PBMC purification from human

and non-human primate blood (NHP), as well as lymphocyte magnetic bead-

based lymphocyte enrichment.

Requirements: Master's degree in immunology, oncology, biology or

related field (willing to accept foreign education equivalent) plus

three (3) years as a research associate with assay development

experience for drug discovery.

Must possess demonstrated expertise in:

•Assay development for cell-based systems;

•Cell culture of mammalian cell lines as well as multiple primary cell

populations;

•Tumor processing and phenotypic characterization; and

•Biomarker and MoA identification studies.

Submit resume to Agenus, Inc., Wendy Baccari, 3 Forbes Road, Lexington,

Massachusetts 02421.

Keywords: Agenus, Inc., Boston , Senior Research Associate, Tumor Immunology, , Lexington, MA, Massachusetts