Senior Payroll & Accounting Specialist

Company: enGene
Location: Boston
Posted on: February 20, 2026

Job Description:

Job Description Job Description enGene (NASDAQ: ENGN) is a late-stage biotechnology company mainstreaming genetic medicines through the delivery of therapeutics to mucosal tissues and other organs, whose lead product candidate, detalimogene voraplasmid, is being evaluated in an ongoing pivotal study for patients with non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (Cis) who are unresponsive to BCG. Detalimogene voraplasmid was developed using enGene’s PROPRIETARY, Dually Derivatized Oligochitosan (DDX) platform, which enables penetration of mucosal tissues and delivery of a wide range of sizes and types of cargo, including DNA and various forms of RNA. For more information, visit enGene.com. Role We are seeking a detail-oriented Payroll & Accounting Specialist to support our growing biotechnology organization. This role is responsible for end-to-end payroll processing, benefits administration, accounts payable, and employee expense reporting. The ideal candidate has hands-on experience with ADP and NetSuite , thrives in a fast-paced biotech environment, and ensures accuracy, compliance, and timely financial operations. ESSENTIAL DUTIES AND RESPONSIBILITIES Payroll & Benefits Process semi-monthly payroll for employees using ADP ,ensuring accuracy and compliance with federal, state, and local regulations Administer employee benefits programs, including medical, dental, vision, 401(k), FSA/HSA, and leave programs Serve as primary point of contact for payroll and benefits inquiries Coordinate payroll-related audits and ensure proper documentation and controls Manage payroll taxes, filings, and reconciliations in coordination with external providers Accounts Payable Oversee full-cycle accounts payable, including vendor setup, invoice processing, approvals, and payments Maintain accurate AP records in NetSuite Reconcile AP subledger to general ledger and resolve discrepancies Support vendor relationships and respond to inquiries Expense Reports Review and process employee expense reports in accordance with company policies Ensure proper coding, approvals, and timely reimbursement Monitor policy compliance and recommend process improvements Accounting & Reporting Prepare and post payroll, benefits, AP, and expense-related journal entries in NetSuite and prepare account reconciliations. Assist with month-end and year-end close activities Support financial audits and internal controls Collaborate cross-functionally with HR, Finance, andOperations teams SKILLS CPP (Certified Payroll Professional) or similar certification Experience with expense management tools (e.g., Concur, Expensify) High attention to detail and strong organizational skills Ability to handle confidential information with discretion REQUIRED EXPERIENCE AND QUALIFICATIONS Minimum Associate’s degree, Bachelor’s Degree preferred in Accounting, Finance, Business Administration, or related field 5 years of experience in payroll, accounting, or finance roles (biotech, life sciences, or startup experience strongly preferred) Hands-on experience with ADP payroll systems and NetSuite ERP Strong knowledge of payroll laws, benefits administration, and accounting principles Experience managing multi-state payroll preferred Location: USA Boston Massachusetts Salary : The salary range for this role is $95,000.00 - $105,000.00 The base salary range provided represents a good faith estimate of the compensation for this position at the time of posting. Actual compensation will be determined based on a number of factors, including, but not limited to, relevant skills, experience and education. enGene USA Inc. is an Equal Opportunity Employer: All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran, or disability status. At enGene USA Inc., we are building a community of intelligent and passionate team members that share our Vision, Mission, and Values, and while the biotechnology space can feel limited in BIPOC, non-binary and even female representation, we endeavor to make hiring decisions that will continue to grow and support our team in the direction of maintaining cultural diversity and sustainability. We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.

Keywords: enGene, Boston , Senior Payroll & Accounting Specialist, Accounting, Auditing , Boston, Massachusetts