BostonRecruiter Since 2001
the smart solution for Boston jobs

Associate Director DMPK Project Lead

Company: Vertex Pharmaceuticals Inc (US)
Location: Boston
Posted on: September 17, 2020

Job Description:

We are seeking an exceptional scientist, leader and cross-functional collaborator to join our Drug Metabolism and Pharmacokinetics (DMPK) team in Boston. The individual serve as the DMPK Project Lead on cross-functional teams and help advance discovery and development of transformational therapies for serious unmet medical needs.

Key Responsibilities:

* Develop and execute scientific strategies to address ADME challenges on discovery and development programs. * Build and maintain strong collaborative partnerships with Medicinal Chemistry, Biology, Preclinical Safety, Clinical Pharmacology, CMC and other R&D disciplines to advance Vertex programs through discovery and development. * Represent DMPK function on drug discovery and development teams and at Vertex R & D governance bodies. * Implement and utilize innovative DMPK technologies and approaches to enhance scientific impact and/or efficiencies. * Provides scientific and managerial leadership to the team in prioritizing and executing on key deliverables and project needs. * Ensure completion of necessary DMPK regulatory documentation and reports to support drug development including Investigator Brochures, INDs (or equivalent), and marketing applications. * Develop internal and external sourcing strategies and liaise across sites to best meet portfolio needs. * Participate in assessment of business development opportunities.

Minimum Requirements:

* PhD or equivalent, with >8 years of experience working in a multifunctional DMPK group in a pharmaceutical company * Successful track record and experience in a DMPK Lead role on multiple R & D teams across more than one therapeutic area. Ability to influence and lead functional and cross-functional colleagues * Broad understanding of the drug discovery and development process and cross-functional dependencies * Deep scientific and strategic expertise various components of predictive and translational DMPK science such as pharmacokinetics, in vitro and in vivo ADME, mass spectrometry and bioanalysis, pharmacokinetic data analysis and interpretation, biotransformation / disposition pathways, drug interaction risk assessment and human pharmacokinetics and dose predictions. Additional skills and familiarity in areas such as transporter science, enzymology, chemistry, and PK/PD and PBPK modeling will be a strong plus. * Ability to stay abreast and critically evaluate scientific literature and new technology as it relates to the discovery and development of new medicines * Excellent verbal, written and interpersonal communication skills, and ability to develop and grow strong cross-site/function collaborations

#LI-BS1

Keywords: Vertex Pharmaceuticals Inc (US), Boston , Associate Director DMPK Project Lead, Executive , Boston, Massachusetts

Click here to apply!

Didn't find what you're looking for? Search again!

I'm looking for
in category
within


Other Executive Jobs


Director, Business Intelligence & Reporting
Description: Director, Business Intelligence Reporting Location Boston, United States Category Data Science Analytics Date posted 11/09/2020 Job ID 2002808 Director, Business Intelligence Reporting - 2002808 (more...)
Company: Santander Group
Location: Boston
Posted on: 09/22/2020

Boston Enterprise Select Account Manager
Description: Job Overview We are looking for an experienced, motivated, and creative Enterprise Select Account Manager to join our team in Boston with a strong Insurance background. You will report to the Regional (more...)
Company: Nutanix
Location: Boston
Posted on: 09/22/2020

Workday Functional Lead Manager
Description: This will navigate you to Accenture.com Sign In page. We are a global collective of innovators applying the New every day to improve the way the world works and lives. New doesn't mean being ahead of (more...)
Company: Accenture
Location: Boston
Posted on: 09/22/2020


GENERAL MANAGER - Woburn, Massachusetts
Description: TheGeneral/Plant Manager has responsibility to drive continuous and significant improvements in safety, quality, delivery and cost by developing an excellent organization, and methodically aggressively (more...)
Company: Tecomet
Location: Wilmington
Posted on: 09/22/2020

Assistant Director of Nursing (ADON) (Registered Nurse/RN)
Description: Live the Mission Position Summary The RN - Assistant Director of Nursing assists the Director of Nursing DON in planning, organizing, developing, and directing the overall operation of the Nursing Services (more...)
Company: Life Care Centers of America
Location: Stoneham
Posted on: 09/22/2020

Product Manager
Description: At Heartify, we are a diverse team of doers, united around the common cause of improving heart health around the world. We are dedicated and passionate about everything we do, and combine a deep understanding (more...)
Company: Heartify Inc.
Location: Boston
Posted on: 09/22/2020

Alpha Implementation Manager - VP
Description: Who we are looking for State Street's Alpha Services Strategy, Solutioning and Implementation Team is seeking a qualified Client Implementation Manager, VP for the industry's first ever front to back (more...)
Company: Acord (association For Cooperative Operations Rese
Location: Boston
Posted on: 09/22/2020

Quality Manager
Description: Job Summary: br br The Quality Manager position provides overall quality leadership and direction to meet customer quality requirements, create, monitor and improve quality programs, reduce quality (more...)
Company: Tecomet
Location: Wilmington
Posted on: 09/22/2020

Fintech Compliance Manager - Pre-paid cards - 20-03681
Description: Job DescriptionFinTech Compliance Manager - Credit CardsMy client is seeking an experienced FinTech compliance professional to ensure the compliant design and implementation of new financial products (more...)
Company: Infinity Consulting Solutions, Inc.
Location: Boston
Posted on: 09/22/2020

Technical Support Manager (Remote) - $100,000/year USD
Description: Are you the best technical support agent in your organization, and want to maximize the impact of your knowledge and experience Do you love helping other support agents deliver exceptional customer experiences (more...)
Company: Crossover for Work
Location: Boston
Posted on: 09/22/2020

Log In or Create An Account

Get the latest Massachusetts jobs by following @recnetMA on Twitter!

Boston RSS job feeds