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Director/Senior Director of Health Economics and Outcomes Research (HEOR)

Company: Krystal Biotech, Inc.
Location: Boston
Posted on: February 25, 2021

Job Description:

Who we are:Krystal Biotech, Inc. is using gene therapy to develop effective and novel treatments for skin diseases. Our goal is to make a meaningful difference in the lives of underserved patient populations with debilitating skin diseases. We work to accomplish that through scientific innovation, operational excellence and believe that "nature operates in the shortest way possible". (Aristotle)Our vision:We strive to be the leader in the development of novel and proprietary "off the shelf" gene therapy products to fight some of the world's most serious skin diseases.Our mission:To develop transformative, innovative, and science-based HSV gene therapy products and processes to dramatically improve people lives.Job Description Summary:Krystal Biotech, Inc. is seeking a highly motivated Director of Health Economics and Outcomes Research (HEOR) who will be responsible for the development of value-based evidence and the development of tools, models and dossiers to support US and Global market access for B-VEC in Dystrophic Epidermolysis Bullosa and other pipeline assets using the Krystal gene delivery platform. The HEOR director will be the key point of contact with authors of outcomes publications and will help lead additional evidence collection to help fill evidence gaps. As B-VEC gets closer to launch the HEOR director will support the development of dynamic tools for the field team to communicate the value of B-VEC to payers and physicians. In addition, the HEOR Director will collaborate with the Clinical R&D team on the development of protocols for Phase II and III assets to ensure necessary economic endpoints are well characterized in the studies including the inclusion of PROs and quality of life metrics.Specific responsibilities include but are not limited to:* Develop health economics evidence and publication plans* Conduct systematic literature review to understand burden of illness of RDEB and D-DEB and develop gap analysis for future studies and support publication of studies* Partner with agency to develop Global Value Dossier, AMCP Dossiers, Cost Effectiveness models, Budget Impact models, and field tools and to localize dossiers for key HTA countries* Partner with patient associations and medical associations to conduct patient and physician surveys with the objective of better categorizing the economic and quality of life burden of RDEB and DDEB* Cross collaborate with Clinical R&D team to ensure HEOR input is included in the design of studies for KB105 and any future assets using the Krystal gene delivery platformThe ideal candidate is/has:* 7-10 years in pharmaceutical industry in a similar role, of which at least 1-2 years in an emerging biotech company* Rare disease experience a plus* Academic degree in health economics and outcomes research (Masters or PhD)Krystal Biotech, Inc. is an Equal Employment Opportunity and Affirmative Action Employers. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender perception or identity, national origin, age, marital status, protected veteran status, or disability status. Headhunters and recruitment agencies may not submit resumes/CVs through this Web site or directly to managers. Krystal Biotech, Inc. does not accept unsolicited headhunter and agency resumes. Krystal Biotech, Inc. will not pay fees to any third-party agency or company that does not have a signed agreement with Krystal Biotech, Inc.Powered by JazzHRli0rOEjB1z

Keywords: Krystal Biotech, Inc., Boston , Director/Senior Director of Health Economics and Outcomes Research (HEOR), Executive , Boston, Massachusetts

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