Executive Director and Head of Structural Biology
Company: Takeda Pharmaceutical
Location: Boston
Posted on: September 30, 2024
Job Description:
By clicking the "Apply" button, I understand that my employment
application process with Takeda will commence and that the
information I provide in my application will be processed in line
with Takeda's and . I further attest that all information I submit
in my employment application is true to the best of my
knowledge.Job DescriptionObjective / Purpose:Takeda is looking for
a well-established transformative leader in the field of structural
Biology to build and lead a state of art, future focused structural
biology organization to support Takeda's pipeline in three
therapeutic areas of interest: Oncology, Gastroenterology &
Immunology, and Neuroscience. The structural biology group will
support drug discovery encompassing three core modalities in small
molecule, biologics and cell therapies. The successful candidate
will lead a team responsible for all structural studies at Takeda
involving X-Ray crystallography, Cryo Electron Microscopy,
structural modeling and AI driven approaches. Proven track record
of team building and leadership along with in depth knowledge of
the structural biology field is essential for this
role.Accountabilities: Scientific Leadership:
- Build, lead and manage a team of structural biologists, protein
scientists, and computational modeling experts.
- Drive scientific excellence in protein structure determination,
molecular modeling, and drug-target interaction validation.
- Collaborate with cross-functional teams (including teams in
Global Biologics, Global Chemistry, therapeutic areas, and
preclinical development) to advance drug discovery projects.Protein
Structure Determination:
- Oversee the design, execution, and interpretation of structural
biology experiments (X-ray crystallography, cryo-EM, etc.).
- Ensure high-quality protein production for structural
studies.
- Apply cutting-edge techniques to elucidate protein-ligand
interactions and conformational dynamics.Computational Modeling:
- Work closely with computational scientists to develop and apply
molecular modeling approaches.
- Utilize structural information to guide drug design and
optimization.Collaboration and Communication:
- Collaborate extensively with internal Takeda stakeholders
- Collaborate with external academic institutions, CROs, and
research partners.
- Present findings at scientific conferences and contribute to
publications.Strategic Planning:
- Define the strategic direction for the Structural Biology
department.
- Align research goals with corporate objectives and therapeutic
areas of interest.Mentoring: Mentor and develop future leaders,
junior scientists, fostering a culture of innovation,
collaboration, and scientific excellence.Program leadership:
Experience in leading discovery programs to development with be
desirableEducation & Competencies (Technical and Behavioral): Ph.D.
in Structural Biology, Biochemistry, or related field. 15+ years
-of relevant experience in pharmaceutical or biotechnology
industry. Proven track record of building and leading successful
structural biology - teams . Track record of supporting biologics,
as well as small molecule programs. Deep and diverse knowledge in
multiple areas of structural biology including X-Ray
crystallography, CryoEM, computational antibody, protein - ligand
modeling and protein chemistry.Excellent leadership, communication,
and interpersonal skills, with the ability to lead a teams,
projects and collaborate effectively across disciplines.Demonstrate
enterprise leadership with an ability to influence without
authority.Established leader in the field as demonstrated by
publications and conference presentationsWell versed on emerging
technologies including realistic implementation of AI/MLThis
position is currently classified as "hybrid" in accordance with
Takeda's Hybrid and Remote Work policy.Takeda Compensation and
Benefits SummaryWe understand compensation is an important factor
as you consider the next step in your career. We are committed to
equitable pay for all employees, and we strive to be more
transparent with our pay practices. -For Location:Boston, MAU.S.
Base Salary Range:$205,100.00 - $322,300.00The estimated salary
range reflects an anticipated range for this position. The actual
base salary offered may depend on a variety of factors, including
the qualifications of the individual applicant for the position,
years of relevant experience, specific and unique skills, level of
education attained, certifications or other professional licenses
held, and the location in which the applicant lives and/or from
which they will be performing the job.---The actual base salary
offered will be in accordance with state or local minimum wage
requirements for the job location. -U.S. based employees may be
eligible for short-term and/ or long-term incentives. U.S. based
employees may be eligible to participate in medical, dental, vision
insurance, a 401(k) plan and company match, short-term and
long-term disability coverage, basic life insurance, a tuition
reimbursement program, paid volunteer time off, company holidays,
and well-being benefits, among others. U.S. based employees are
also eligible to receive, per calendar year, up to 80 hours of sick
time, and new hires are eligible to accrue up to 120 hours of paid
vacation. -EEO StatementTakeda is proud in its commitment to
creating a diverse workforce and providing equal employment
opportunities to all employees and applicants for employment
without regard to race, color, religion, sex, sexual orientation,
gender identity, gender expression, parental status, national
origin, age, disability, citizenship status, genetic information or
characteristics, marital status, status as a Vietnam era veteran,
special disabled veteran, or other protected veteran in accordance
with applicable federal, state and local laws, and any other
characteristic protected by law.LocationsBoston, MAWorker
TypeEmployeeWorker Sub-TypeRegularTime TypeFull time
Keywords: Takeda Pharmaceutical, Boston , Executive Director and Head of Structural Biology, Executive , Boston, Massachusetts
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