Research Associate I/II, Neuromuscular and Cardiac Biology

Company: Mix Talent
Location: Boston
Posted on: January 16, 2022

Job Description:

Job Description Mix Talent is a specialty life sciences-focused talent and consulting firm, and we partner with pharma, biotech, and gene therapy client companies across the United States and beyond. We support clients throughout the drug discovery and development lifecycle and work with candidates from executive search through entry level and everyone in-between. The R&D Recruitment Team at Mix Talent specializes in uniting passionate scientists and visionary leaders with start-ups and well-established pharma and biotech companies who value and support employee growth as they strive to develop novel, cutting-edge therapies. Mix Talent has partnered with a growing biotech company based in Boston, MA and we are looking for a passionate Research Associate I/II. In this position you will be involved in all aspects of neuromuscular and cardiac biology. You should have hands-on experience in pre-clinical in vivo research involving genetic mouse or rat models and enjoy a combination of hands-on rodent work and ex vivo tissue processing and analysis. You must be skilled in mouse/rat handling (colony management, genotyping, dosing, tissue collection). Familiarity with ex-vivo assays such as DNA, RNA and protein preparation, qRT-PCR, Western blot, and IHC analysis is helpful but not required. Your team player mentality and excellent communication skills will allow you to collaborate effectively as you work alongside your team as well as cross-functionally. Additionally, you will play a critical role in both in vivo and ex vivo aspects of pre-clinical POC studies including functional testing. Responsibilities Plan and execute preclinical proof of concept studies utilizing multiple genetic mouse and rat models of neuromuscular and cardiac diseases. Utilize in vivo skills including rodent handling, colony management, genotyping, drug treatment (IV (tail vein), IP, IT, SC, and ICV routes), and tissue collection (blood, muscle, brain, CSF and other tissues). Execute and troubleshoot ex vivo assays and techniques including DNA, RNA and protein preparation, qRT-PCR, Western blot, and IHC. Interpret and present research data and findings in internal scientific meetings. Effectively collaborate and communicate in a fast-paced, multi-disciplinary environment. Be scientifically curious and self-driven with good time management skills. Document work in a well-maintained lab notebook. Qualifications B.S./M.S. in Molecular/Cellular biology or a related field with 0-2 years of relevant academic or industry experience for the RA I or 2 years of experience for the RA II position Proficiency in rodent dosing (IV (tail vein), IP, IT, SC, and ICV routes), blood/CSF collection, and tissue collection is required. Hands-on experience with ex vivo sample processing including DNA, RNA, and protein extractions is desired. Demonstrated ability to run PCR, qPCR, western blot, and IHC is preferred, but not required. Foundational knowledge of skeletal/cardiac muscle biology is a plus Excellent verbal and written communication skills LI-216191156_

Keywords: Mix Talent, Boston , Research Associate I/II, Neuromuscular and Cardiac Biology, Healthcare , Boston, Massachusetts