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Bioinformatics Software Engineer

Company: Vertex Pharmaceuticals
Location: Boston
Posted on: May 28, 2023

Job Description:

Bioinformatics Software Engineer page is loaded Bioinformatics Software Engineer Apply locations Boston, MA time type Full time posted on Posted 2 Days Ago job requisition id REQ-19149 Job DescriptionWe are seeking a highly motivated and experienced computational biologist with a strong software engineering background to join Vertex. This position is part of a rapidly growing Data and Computational Sciences team focused on Cell and Genetic therapies for diseases with serious unmet need. You will play a critical key role in developing cutting-edge computational methods that assess the safety and efficacy of transformative gene editing therapeutics for our program. You will also cross-functionally collaborate to develop robust, efficient, and scalable workflows that can be easily maintained and executed on a large scale. A strong background in computational methods development, a proven track record in python programming and an ability to seamlessly collaborate with team members will be required for success in this role. This is a Boston based, hybrid position (3 days/week onsite).
-Key responsibilities:

  • Develop novel computational methods that address key questions regarding the efficacy and safety of gene editing therapeutics.
  • Leverage and extend best practices from the genomics, data science and software-engineering to create industry-leading analysis software.
  • Develop automated, scalable solutions that accelerate discovery.
  • Collaborate with project teams to identify key needs and questions that can be addressed using genomics.Education and Experience:
    • Ph.D. (or equivalent degree) in computational biology, bioinformatics, human genetics, genomics, systems biology, bioengineering, or a related field, and 0-3 years of relevant post-doctoral employment experience, or
    • Master's Degree (or equivalent degree) in similar fields and 3+ years of relevant employment experience, or
    • Bachelor's Degree (or equivalent degree) in similar fields and 6+ years of relevant employment experience
    • A proven track record of next-generation sequencing (NGS) methods development pertaining to variant calling, RNA-Seq, amplicon sequencing or related data types.
    • Strong programming skills in python and one or more of the following languages: Rust, Java or C/C++, and proficiency with workflow languages such as Nextflow
    • Demonstrated experience with cloud computing platforms (AWS preferred) and their associated services (S3, EC2, Batch Lambda, etc.)
    • Strong understanding of database design principles and integration
    • Experience with containerization technologies such as Docker or Singularity
    • Understanding of software engineering practices such as source control, unit testing and continuous integration
    • An independent, detail-oriented, and self-motivated approach to problem solving
    • A team-oriented mindset that welcomes feedback and supports others
    • Strong organizational and time-management skills#LI-SV1#LI-HybridCompany Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com. About Us Help Us Achieve Our Mission Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has multiple approved medicines that treat the underlying cause of cystic fibrosis (CF) - a rare, life-threatening genetic disease - and has several ongoing clinical and research programs in CF. Beyond CF, Vertex has a robust pipeline of investigational small molecule, cell and genetic therapies in other serious diseases where it has deep insight into causal human biology, including sickle cell disease, beta thalassemia, APOL1-mediated kidney disease, pain, type 1 diabetes, alpha-1 antitrypsin deficiency and Duchenne muscular dystrophy.Founded in 1989 in Cambridge, Mass., Vertex's global headquarters is now located in Boston's Innovation District and its international headquarters is in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia and Latin America. Vertex is consistently recognized as one of the industry's top places to work, including 13 consecutive years on Science magazine's Top Employers list and one of Fortune's Best Workplaces in Biotechnology and Pharmaceuticals and Best Workplaces for Women. For company updates and to learn more about Vertex's history of innovation, visit www.vrtx.com -or follow us on Facebook , - Twitter , - LinkedIn , - YouTube -and - Instagram . The diversity and authenticity of our people is part of what makes Vertex unique, and we recognize that each employee brings diverse perspectives and strengths. By embracing those strengths and celebrating differences, we are fostering an inclusive culture where each of us can bring our authentic selves to work, inspire innovation together, and change people's lives. -Our vision is clear: to be the place where an authentic, diverse mix of talent want to come, to stay, and do their best work.

Keywords: Vertex Pharmaceuticals, Boston , Bioinformatics Software Engineer, IT / Software / Systems , Boston, Massachusetts

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