Principal Data Engineer
Company: Takeda
Location: Boston
Posted on: February 22, 2026
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Job Description:
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that all information I submit in my employment application is true
to the best of my knowledge. Job Description Pursuant to Section 20
C.F.R. 656.10, you are hereby notified that an application for
Alien Employment Certification will be filed by Takeda Development
Center Americas, Inc. for the following job opportunity: JOB
LOCATION: Cambridge, MA POSITION : Principal Data Engineer POSITION
DESCRIPTION : Takeda Development Center Americas, Inc. is seeking a
Principal Data Engineer with the following duties: engineer
cloud-based data pipelines using Python, Spark, and Airflow to
automate ETL/ELT processes, enabling efficient data ingestion,
transformation, and storage across data lakes and warehouses;
design and implement AI/ML and GenAI-driven solutions using
supervised/unsupervised learning, statistical modeling, and NLP to
enhance data quality, automate workflows, detect similarities, and
support evidence-based clinical decision-making; develop robust
data integration workflows for structured and unstructured data,
ensuring adherence to Good Clinical Practices (GCP), FDA
regulations, and SOPs through SQL-based data validation frameworks;
create interactive dashboards and real-time visualization platforms
to deliver actionable insights from clinical and operational data,
enabling stakeholders to monitor performance and drive
data-informed strategies; develop custom automation tools using
Python, R, and APIs to streamline data entry, reduce manual
processing, and enhance operational efficiency across clinical
research systems; drive strategic alignment by partnering with
crossfunctional teams, mentoring junior engineers, and advising
leadership on AI/ML adoption, automation strategies, and emerging
data technologies; influence industry practices by presenting
technical innovations at leading conferences and guiding
enterprise-wide adoption of scalable, AI-powered data engineering
solutions. 100% remote work allowed anywhere in the U.S. The
estimated salary range reflects an anticipated range for this
position. The actual base salary offered will be in accordance with
state or local minimum wage requirements for the job location. U.S.
based employees may be eligible for short-term and/or long-term
incentives. U.S. based employees may be eligible to participate in
medical, dental, vision insurance, a 401(k) plan and company match,
short-term and long-term disability coverage, basic life insurance,
a tuition reimbursement program, paid volunteer time off, company
holidays, and well-being benefits, among others. U.S. based
employees are also eligible to receive, per calendar year, up to 80
hours of sick time, and new hires are eligible to accrue up to 120
hours of paid vacation. REQUIREMENTS: Master’s degree in Computer
Science, Data Science, Engineering, or related field, plus 30
months of related experience. Prior experience must include:
design, develop, test, and deploy software applications and
features based on client and project requirements; implement
automated testing and regression testing using Selenium and Python
to improve test coverage, reduce manual effort, and ensure
application stability; collaborate with cross-functional teams,
including developers, business analysts, and QA leads, to identify
test requirements and participate in Agile/Scrum ceremonies to
plan, deliver, and communicate software progress iteratively;
perform data wrangling, transformation, and management to create
structured datasets stored in databases, supporting data analyses.
Full time. $139,000 - $236,800 per year. Qualified applicants can
apply at https://jobs.takeda.com . Please reference job R0174687.
EOE Any individual may provide documentary evidence bearing on this
application, with information on available workers and information
on wages and working conditions, to the Certifying Officer, U.S.
Department of Labor, Employment and Training Administration, Office
of Foreign Labor Certification, 200 Constitution Avenue, NW, Room
N-5311, Washington, DC 20210. Locations Boston, MA Worker Type
Employee Worker Sub-Type Regular Time Type Full time
Keywords: Takeda, Boston , Principal Data Engineer, IT / Software / Systems , Boston, Massachusetts
