Company: Yoh, A Day & Zimmermann Company
Posted on: April 10, 2021
Location: Waltham, MA
Client is a startup biotech seeking to revolutionize life-changing
therapeutics for patients by identifying novel T cells and
epitopes. We are looking for an experienced researcher to join our
team as a Scientist, supporting our novel target identification and
validation workflow in house. The ideal candidate should have
relevant experience in primary T cell culture, immunoassays, flow
cytometry, and molecular biology, and enjoy fast-paced,
collaborative and vibrant startup culture. A team player with a
sense of urgency will thrive in this role.
Duties of position:
--- Engage and innovate on large-scale in vitro immune cell
screening efforts to discover novel TCRs to fuel our therapeutic
--- Isolate PBMCs, primary T cells, and monocytes from blood
products such as leukopaks, differentiate monocytes to DCs, and
perform T cell-DC co culture assays.
--- Evaluate and nominate candidate TCRs discovered from our
screens for preclinical development. Candidate to perform in vitro
immune assays such as tumor cell killing, cytokine production and T
--- Evaluate novel targets to be pursued in TCR discovery pipeline,
and assist in platform development for discovery of TCRs specific
for multiple targets.
--- Candidate to analyze data and present and group and company
--- Ph.D. with 0-2 years of relevant post-doc, biopharmaceutical or
biotechnology industry experience, or MS/BS with 7-10 years
relevant experience. Demonstrated record of scientific achievement
(strong publication and/or patent record).
--- Extensive experience in T cell immunology required;
understanding of dendritic cell biology, cancer biology and
molecular biology a plus.
--- Expertise in tissue culture, flow cytometry, and cell
engineering required. Proficiency in immunological techniques such
as ELISA and cytotoxicity assays using Incucyte desired.
--- Excellent communication skills (both written and oral) and
ability to work in a matrix environment.
Yoh, a Day & Zimmermann company, is an Equal Opportunity Employer.
All qualified applicants will receive consideration for employment
without regard to race, color, religion, sex, sexual orientation,
gender identity, national origin, disability, or status as a
protected veteran. Visit
https://www.yoh.com/applicants-with-disabilities to contact us if
you are an individual with a disability and require accommodation
in the application process.PandoLogic.Category: Science, Keywords:
Keywords: Yoh, A Day & Zimmermann Company, Boston , Scientist, Other , Waban, Massachusetts
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