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Research Associate - In Vivo

Company: Dana-Farber Cancer Institute
Location: Boston
Posted on: June 12, 2021

Job Description:

Overview

The Robert and Rene Belfer Center for Applied Cancer Science at the Dana-Farber Cancer Institute is an integrative research center that is dedicated to translating basic discoveries into new effective therapies for cancer patients. We partner with industry and Dana-Farber Physician Scientists and apply industrial capabilities to cutting edge clinical problems. As part of our growing team, we are seeking highly motivated bench-level scientists for our in vivo team.

For more information please visit: http://belfercenter.dfci.harvard.edu

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

Responsibilities

Job Responsibilities

  • Job Responsibilities

Assist with the establishment and maintenance of mouse cancer models (e.g. by injection or minor / major surgery).

  • Build of syngeneic, xenograft, PDX and orthotopic mouse cancer models
  • Perform mouse in vivo animal procedures, including dosing animals by various routes (e.g. oral, intravenous, intraperitoneal, etc), measuring tumors by calipers, non-invasive imaging (bioluminescent imaging)
  • Perform efficacy and tolerability testing in mouse cancer models
  • Breeding and genotyping of GEMMs
  • Animal health monitoring
  • Mouse necropsy and tissue collection
  • Routine handling, restraint, identification (including ear notching, tagging, tattooing, and toe clipping) and sexing of common laboratory animals. Ability to distinguish various common laboratory animal strains in accordance with standardized genetic nomenclature and phenotype identification.
  • Cell culturing techniques and subcutaneous implantation of cell and tumor grafts
  • Data recording, data analysis, reporting and interpretation
  • Contribute to overall vivarium organization and IACUC protocol

Qualifications

Minimum Qualifications

  • BS in biological sciences or equivalent
  • LAT certification preferred
  • 1-2 year research experience in academic and/or pharmaceutical/biotech environment preferred
  • Ability to work in a team environment

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.

Keywords: Dana-Farber Cancer Institute, Boston , Research Associate - In Vivo, Other , Boston, Massachusetts

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