Bioassay Scientist

Company: Takeda Pharmaceutical
Location: Canton
Posted on: September 25, 2022

Job Description:

By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. Job Description At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on four therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.Join Takeda as a Bioassay Scientist where you will responsible for designing and executing laboratory experiments to support the development, qualification, and automation of potency assays, including cell- based methods. You will also focus on the development of methods supporting biological therapeutic product release and characterization in a compliance-based environment. As part of the Discovery Research team, you will report to Potency and Functional Characterization Group Lead. How you will contribute:

• Design and execute laboratory experiments to support method development and automation.
• Design and participate in the qualification and transfer of potency methods.
• Author and review technical documents such as protocols, SOPs, and reports.
• Troubleshoot complex cell-based potency methods.
• Manage outsourced activities pertaining to potency development, validation and testing.
• Present data/results in group and department meetings.
• Sample testing to support process and formulation development.
• Perform general laboratory and equipment maintenance according to established schedules as needed. Minimum Requirements/Qualifications:
  • Ph.D. in Biology, Biochemistry or related discipline with 0 - 3 years of relevant postdoctoral or industry experience.
  • MS in Biology, Biochemistry or related discipline with 3 years relevant industry experience.
  • BS in Biology, Biochemistry or related discipline with 8 years relevant industry experience.
  • In-depth understanding of relevant guidelines (ICH, USP 1032, 1033, 1034).
  • In-depth knowledge of theories/principles not limited to: performance of tissue culture, aseptic technique, potency methods (including cell-based, binding, and ELISA platforms).
  • Experience troubleshooting and optimizing cell-based potency assays desired.
  • Experience automating plate-based potency methods.
  • Experience overseeing outsourced analytical activities and collaborating with external partners desirable.
  • Familiarity with applicable regulatory guidelines (ICH, USP, EP), specifically as they pertain to potency assays desired.
  • Familiarity with software packages such as SoftMax, GraphPad, PLA, and JMP preferred. Experience with automated liquid handling platforms such as the Hamilton Star or Vantage desired.
  • Familiarity with SPR, BLI, flow cytometry, and qPCR desired.
  • Experience developing stable analytical cell lines for reporter gene applications and elevated protein expression desired. What Takeda can offer you:
    • Comprehensive Healthcare: Medical, Dental, and Vision
    • Financial Planning & Stability: 401(k) with company match and Annual Retirement Contribution Plan
    • Health & Wellness programs including onsite flu shots and health screenings
    • Generous time off for vacation and the option to purchase additional vacation days
    • Community Outreach Programs and company match of charitable contributions
    • Family Planning Support
    • Flexible Work Paths
    • Tuition reimbursement More about us: At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world. This position is currently classified as "hybrid" in accordance with Takeda's Hybrid and Remote Work policy. In accordance with the CO Equal Pay Act, Colorado Applicants Are Not Permitted to Apply. EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. Locations Lexington, MA Worker Type Employee Worker Sub-Type Regular Time Type Full time

Keywords: Takeda Pharmaceutical, Boston , Bioassay Scientist, Other , Canton, Massachusetts