Research Scientist, Liver Disease
Company: Takeda Pharmaceutical
Location: Boston
Posted on: September 30, 2024
Job Description:
By clicking the "Apply" button, I understand that my employment
application process with Takeda will commence and that the
information I provide in my application will be processed in line
with Takeda's and . I further attest that all information I submit
in my employment application is true to the best of my
knowledge.Job DescriptionResearch Scientist, Liver Disease About
the role:At Takeda, we are a forward-looking, world-class R&D
organization that unlocks innovation and delivers transformative
therapies to patients. By focusing R&D efforts on three
therapeutic areas and other targeted investments, we push the
boundaries of what is possible in order to bring life-changing
therapies to patients worldwide.Join Takeda as a Research
Scientist, Liver Disease Research where you will be part of a team
focused on validation of novel targets and the evaluation of drug
candidates for the treatment of chronic fibroinflammatory liver
diseases.How you will contribute:
- You will apply expertise in executing in vitro studies relevant
to fibroinflammatory liver disease biology and pharmacology.
- You will play a central role in generating key data for
evaluating potential targets, mechanism of action and/or drug
candidate efficacy and pharmacodynamics.
- You will need to be a highly collaborative and energetic team
player and a self-directed learner with a keen interest in focused,
fast-paced research.
- Designs and executes relevant target and drug candidate
validation studies using contemporary methods and tools.
- Using a broad range of technologies, determine mechanism of
action for drug targets and candidates with appropriate
controls
- Implement target-specific assays to assess target and drug
activity in vitro and/or in vivo, as appropriate
- Identifies orthogonal applications of target, pathway, or
platform biology in other fibroinflammatory diseases
- Participate on cross-functional teams and provide technical
leadership in area of expertise; may lead an initiative or one of a
broader scope with a less-defined outcome
- Prepare technical reports, summaries, protocols, and
quantitative analyses in written and/or oral form
- Proactively identify complex obstacles to progress in specific
areas; recommend and implement solutions using a diverse set of
resources; regularly add value to research projects through
creative ideas
- Manage a wide variety of tasks, techniques, and projects;
integrate these responsibilities to produce quality result with a
high level of efficiency; may act as a scientific mentor to
others
- Keep an accurate, comprehensible, concise notebook in
accordance with company policy
- Maintain lab equipment and supplies as needed
- Maintain a safe and organized lab bench
- Communicate with colleagues effectively
- Present data to other scientific staff or cross-functional
project team; may present data/posters to external research or
scientific community.Minimum Requirements/Qualifications:
- PhD degree in a scientific discipline (or equivalent), orMS
with 6+ years relevant experience, or BS with 8+ years relevant
experience in vitro drug discovery research
- Demonstrated ability to independently solve scientific problems
using multiple, state-of-the-art technologies and approaches -
- Significant experience with drug discovery applications of cell
culture including immortalized cell lines, primary cell cultures,
and multicellular or organoid culture models, preferably models
that recapitulate cellular cross-talk in fibroinflammatory or
diseased tissues
- Expertise in at least one of the following assay methods:
ELISA, Western blot, qPCR, flow cytometry, ChIP
- Experience and continued willingness to work with live rodents
and animal tissue
- Demonstrates exceptional project management skills and in-depth
in vitro cell and molecular biology assay experience - - -Takeda
Compensation and Benefits SummaryWe understand compensation is an
important factor as you consider the next step in your career. We
are committed to equitable pay for all employees, and we strive to
be more transparent with our pay practices. -For Location:Boston,
MAU.S. Base Salary Range:$108,500.00 - $170,500.00The estimated
salary range reflects an anticipated range for this position. The
actual base salary offered may depend on a variety of factors,
including the qualifications of the individual applicant for the
position, years of relevant experience, specific and unique skills,
level of education attained, certifications or other professional
licenses held, and the location in which the applicant lives and/or
from which they will be performing the job.---The actual base
salary offered will be in accordance with state or local minimum
wage requirements for the job location. -U.S. based employees may
be eligible for short-term and/ or long-term incentives. U.S. based
employees may be eligible to participate in medical, dental, vision
insurance, a 401(k) plan and company match, short-term and
long-term disability coverage, basic life insurance, a tuition
reimbursement program, paid volunteer time off, company holidays,
and well-being benefits, among others. U.S. based employees are
also eligible to receive, per calendar year, up to 80 hours of sick
time, and new hires are eligible to accrue up to 120 hours of paid
vacation. -EEO StatementTakeda is proud in its commitment to
creating a diverse workforce and providing equal employment
opportunities to all employees and applicants for employment
without regard to race, color, religion, sex, sexual orientation,
gender identity, gender expression, parental status, national
origin, age, disability, citizenship status, genetic information or
characteristics, marital status, status as a Vietnam era veteran,
special disabled veteran, or other protected veteran in accordance
with applicable federal, state and local laws, and any other
characteristic protected by law.LocationsBoston, MAWorker
TypeEmployeeWorker Sub-TypeRegularTime TypeFull time
Keywords: Takeda Pharmaceutical, Boston , Research Scientist, Liver Disease, Other , Boston, Massachusetts
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